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Partial characterisation of a sex-steroid binding protein in plasma from Svalbard charr (Salvelinus alpinus L.)
Øvrevik, J.; Tollefsen, K.-E.; Nilssen, K.; Stenersen, J. (2000). Partial characterisation of a sex-steroid binding protein in plasma from Svalbard charr (Salvelinus alpinus L.), in: Norberg, B. et al. (Ed.) Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. pp. 378
In: Norberg, B. et al. (2000). Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. International Symposium on the Reproductive Physiology of Fish, 6. Department of Fisheries and Marine Biology, University of Bergen: Bergen. ISBN 82-7461-048-2. 499 pp., meer
In: International Symposium on the Reproductive Physiology of Fish. Museo Nacional de Ciencias Naturales. , meer
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  • Øvrevik, J.
  • Tollefsen, K.-E.
  • Nilssen, K.
  • Stenersen, J.
Abstract
    A single 100 kDa sex-steroid binding protein (SBP) that binds both 17 beta -estradiol and testosterone was identified in plasma from Svalbard charr (Salvelinus alpinus L). Tritiated 17 beta -estradiol was bound with high affinity and high capacity (K sub(d)=0.5-4 nM and B sub(max)=400-1300 fmol/mg protein) to a single binding site. In addition to endogenous hormones several xenoestrogens were able to compete for binding to the sex-steroid binding site.
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