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Toxicity of medicinal plants used in traditional medicine in Northern Peru
Bussmann, R.W.; Malca, G.; Glenn, A.; Sharon, D.; Nilsen, B.; Parris, B.; Dubose, D.; Ruiz, D.; Saleda, J.; Martinez, M.; Carillo, L.; Walker, K.; Kuhlman, A.; Townesmith, A. (2011). Toxicity of medicinal plants used in traditional medicine in Northern Peru. Journal of Ethnopharmacology 137(1): 121-140. https://dx.doi.org/10.1016/j.jep.2011.04.071
In: Journal of Ethnopharmacology. Elsevier Science Ireland: Shannon. ISSN 0378-8741, meer
Peer reviewed article  
Beschikbaar in  Auteurs 
Trefwoord
    Artemia salina (Linnaeus, 1758) [WoRMS]
Author keywords
    medicinal plants, ethnobotany, brine shrimp, Artemia salina, toxicity, Northern Peru
Auteurs  Top 
  • Bussmann, R.W.
  • Malca, G.
  • Glenn, A.
  • Sharon, D.
  • Nilsen, B.
  • Parris, B.
  • Dubose, D.
  • Ruiz, D.
  • Saleda, J.
  • Martinez, M.
  • Carillo, L.
  • Walker, K.
  • Kuhlman, A.
  • Townesmith, A.
Abstract

    Aim

    The plant species reported here are traditionally used in Northern Peru for a wide range of illnesses. Most remedies are prepared as ethanol or aqueous extracts and then ingested. The aim of this study was to evaluate the potential toxicity of these extracts.

    Materials and methods

    The toxicity of ethanolic and water extracts of 341 plant species was determined using a Brine-Shrimp assay.

    Results

    Overall 24% of the species in water extract and 76% of the species in alcoholic extract showed elevated toxicity levels to brine-shrimp. Although in most cases multiple extracts of the same species showed very similar toxicity values, in some cases the toxicity of different extracts of the same species varied from non-toxic to highly toxic.

    Conclusions

    Traditional preparation methods take different toxicity levels in aqueous and ethanol extracts into account when choosing the appropriate solvent for the preparation of a remedy.

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