The reaction of the immune system of fish to vaccination
Lamers, C. (1985). The reaction of the immune system of fish to vaccination. PhD Thesis. PUDOC: Wageningen. 256 pp.
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Documenttype: Doctoraat/Thesis/Eindwerk
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| Abstract |
The studies presented in this thesis deal with the effect of bacterial antigens of Yersinia ruckeri and Aeromonashydrophila on the immune system of carp. The antigens were administered by injection or by bath treatment. The effect on the immune system was studied by measuring the numbers of antibody forming cells (AFCs), the level of serum antibody and the processing of antigen in the lymphoid organs. The antigen dose and the formation of immunological memory were taken into account. Moreover, in view of oral vaccination, a study was carried out on the uptake and transport of macromolecules through the intestinal epithelial cells. |
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