Bioactive compounds isolated from neglected predatory marine gastropods
Turner, A.; Craik, D.J.; Kaas, Q.; Schroeder, C.I. (2018). Bioactive compounds isolated from neglected predatory marine gastropods. Mar. Drugs 16(4): [1-20]. https://dx.doi.org/10.3390/md16040118
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, meer
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| Trefwoorden |
Chemical compounds > Organic compounds > Proteins > Peptides
Toxins
Gastropoda [WoRMS]; Ranellidae J. E. Gray, 1854 [WoRMS]
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| Author keywords |
marine gastropods; salivary glands; echotoxins |
| Auteurs | | Top |
- Turner, A.
- Craik, D.J.
- Kaas, Q.
- Schroeder, C.I.
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| Abstract |
A diverse range of predatory marine gastropods produce toxins, yet most of these molecules remain uncharacterized. Conus species have received the most attention from researchers, leading to several conopeptides reaching clinical trials. This review aims to summarize what is known about bioactive compounds isolated from species of neglected marine gastropods, especially in the Turridae, Terebridae, Babyloniidae, Muricidae, Buccinidae, Colubrariidae, Nassariidae, Cassidae, and Ranellidae families. Multiple species have been reported to contain bioactive compounds with potential toxic activity, but most of these compounds have not been characterized or even clearly identified. The bioactive properties and potential applications of echotoxins and related porins from the Ranellidae family are discussed in more detail. Finally, the review concludes with a call for research on understudied species. |
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