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Études sur la tolérabilité des onguents contenant un principe actif extrait de Trygon pastinaca
Busuricu, F.; Antohi, I. (1998). Études sur la tolérabilité des onguents contenant un principe actif extrait de Trygon pastinaca. Cercet. Mar./Rech. Mar. 31: 219-222
In: Cercetari Marine = Recherches Marines. Institutul Naţional de Cercetare-Dezvoltare Marină Grigore Antipa: Constanta. ISSN 0250-3069, meer
Peer reviewed article  
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  • Busuricu, F.
  • Antohi, I.
Abstract
    The basic element isolated from Trygon pastinaca can be used as dermatologic creams having a photoprotective and antioxidating action. Tolerableness tests of some ointments including the marine originated active basic element have been carried out. The active basic element of various concentrations (1.5 and 3%) was incorporated in three bases of different ointments: two bases for the stability of A and D hydrodispersed vitamins, and a base for the stability of A and D vitamin acetate. The acanthosis test and the test directly applied on skin have been made. The results show that the ointment bases including the marine extract have been well tolerated both by the rats and human patients tested; consequently that extract can be used in obtaining dermatologic or cosmetic creams.
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