Trained as a computational biologist in the field of development and evolution (Universidad de Antioquia, BSc. and MSc.) and biochemistry and biotechnology with a focus on evolutionary systems biology (Ghent University, PhD.). More than 9 years of expertise in developing and applying systems biology-oriented mathematical modeling, evolutionary algorithms and combinatorial optimization methods, multimodal data analysis and visualization methods. Ability to deploy across high performance computing systems sophisticated mathematical modeling frameworks, data analysis pipelines and bioinformatics workflows to address complex biological phenomena. Thesaurusterm: Computationele biomodellering en machine learning
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Vlaams Instituut voor de Zee (VLIZ), meer
Functie: Senior Onderzoeker
Contact op het instituut:
Tel.: +32-(0)59-33 61 26
GSM: +32-(0)492 92 59 02
E-mail:
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Vlaams Instituut voor Biotechnologie; VIB-Ugent Centrum voor Plantaardige systeembiologie (PSB), meer
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- PPDB: Gutierrez, J.; Hablützel, P.I.; Flanders Marine Institute: Belgium; (2022): Plankton-specific protein sequence database. Marine Data Archive., meer
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A1 publicaties (5) [show] |
- Arboleda-Rivera, J.C.; Machado-Rodríguez, G.; Rodríguez, B.A.; Gutiérrez, J. (2022). Elucidating multi-input processing 3-node gene regulatory network topologies capable of generating striped gene expression patterns. PLoS computational biology 18(2): e1009704. https://dx.doi.org/10.1371/journal.pcbi.1009704, meer
- Fernandez, G.J.; Ferreira, J.H.; Vechetti, I.J.; de Moraes, L.N.; Cury, S.S.; Freire, P.P.; Gutiérrez, J.; Ferretti, R.; Dal-Pai-Silva, M.; Rogatto, S.R.; Carvalho, R.B. (2020). MicroRNA-mRNA co-sequencing identifies transcriptional and post-transcriptional regulatory networks underlying muscle wasting in cancer Cachexia. Frontiers in Genetics 11: 541. https://dx.doi.org/10.3389/fgene.2020.00541, meer
- Gutiérrez, J.; Maere, S. (2014). Modeling the evolution of molecular systems from a mechanistic perspective. Trends Plant Sci. 19(5): 292-303. https://dx.doi.org/10.1016/j.tplants.2014.03.004, meer
- Gutiérrez, J.; St Laurent, G.; Urcuqui-Inchima, S. (2010). Propagation of kinetic uncertainties through a canonical topology of the TLR4 signaling network in different regions of biochemical reaction space. Theoretical Biology and Medical Modelling 7: 7. https://dx.doi.org/10.1186/1742-4682-7-7, meer
- Gutiérrez, J. (2009). A developmental systems perspective on epistasis: computational exploration of mutational interactions in model developmental regulatory networks. PLoS One 4(9): e6823. https://dx.doi.org/10.1371/journal.pone.0006823, meer
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Thesis [show] |
- Gutiérrez, J. (2014). Deciphering the evolutionary impact of gen(om)e duplications through mechanistic modeling of the genotypephenotype map. PhD Thesis. Ghent University. Faculty of Sciences: Ghent. [diff. pag.] pp., meer
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Abstracts (3) [show] |
- Gutiérrez, J.; Hablützel, P. (2023). A system-level view on the function of natural eukaryotic biomes through taxonomically resolved metabolic pathway profiling, in: 54th International Liège Colloquium on Ocean Dynamics: machine learning and data analysis in oceanography. pp. 1, meer
- Gutiérrez, J.; Hablützel, P. (2022). Customizing sequence databases for system level analysis of gene expression in marine microbial plankton, in: Mees, J. et al. Book of abstracts – VLIZ Marine Science Day, Online event 2 March 2022. VLIZ Special Publication, 88: pp. 52, meer
- Gutiérrez, J. (2020). A genomically-explicit evolutionary modeling approach to study metapopulation adaptive responses under arbitrary connectivity, in: Mees, J. et al. Book of abstracts – VLIZ Marine Science Day. Oostende, Belgium, 18 March 2020. VLIZ Special Publication, 84: pp. 57, meer
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Overige publicaties (2) [show] |
- Gutiérrez, J.; Hablützel, P. (2022). A system-level view on the function of natural eukaryotic biomes through taxonomically resolved metabolic pathway profiling. bioRxiv Preprint: 1-23. https://dx.doi.org/10.1101/2022.07.27.501711, meer
- Arboleda-Rivera, J.C.; Machado-Rodríguez, G.; Rodríguez, B.A.; Gutiérrez, J. (2021). Elucidating multi-input processing 3-node gene regulatory network topologies capable of generating striped gene expression patterns. bioRxiv 2021: 1-24. https://dx.doi.org/10.1101/2021.11.01.466847, meer
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