| one publication added to basket [4219] | Gonadal steroid hormones: major regulators of gonadal sex differentiation and gametogenesis in fish
Nagahama, Y. (2000). Gonadal steroid hormones: major regulators of gonadal sex differentiation and gametogenesis in fish, in: Norberg, B. et al. Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. pp. 211-222
In: Norberg, B. et al. (2000). Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. International Symposium on the Reproductive Physiology of Fish, 6. Department of Fisheries and Marine Biology, University of Bergen: Bergen. ISBN 82-7461-048-2. 499 pp., more
In: International Symposium on the Reproductive Physiology of Fish. Museo Nacional de Ciencias Naturales. , more
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- Nagahama, Y., correspondent
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| Abstract |
In all vertebrates, steroid hormones are major mediators of sexual differentiation and gametogenesis. Their effects are particularly profound in teleosts fishes which provide several excellent models for investigating the basic hormonal mechanisms regulating gonadal sex differentiation and gametogenesis. In this article, I will present a brief overview of our current understanding of these mechanisms based on research in several teleost fish models. The synthesis, sites of action, and major mediators are described for three critical steroid hormones, estradiol-17 beta (ovarian formation and oocyte growth), 11-ketotestosterone (spermatogenesis) and 17 alpha ,20 beta -dihydroxy-4-pregnen-3-one (gamete maturation). These findings, combined with those of other laboratories investigating teleost fishes, represent one of the best documented examples of the roles of steroid hormones in vertebrate gonadal sex differentiation and gametogenesis and may provide valuable insight into conserved mechanisms of action. |
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