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A fully automated method for late ventricular diastole frame selection in post-dive echocardiography without ECG gating
Markley, E.; Le, D.Q.; Germonpré, P.; Balestra, C.; Tillmans, F.; Denoble, P.J.; Freiberger, J.J.; Moon, R.E.; Dayton, P.A.; Papadopoulou, V. (2021). A fully automated method for late ventricular diastole frame selection in post-dive echocardiography without ECG gating. Undersea Hyperb. Med. 48(1): 73-80
In: Undersea and Hyperbaric Medicine. The Society: Bethesda, Md.. ISSN 1066-2936, more
Peer reviewed article  

Available in  Authors 

Author keywords
    echocardiography; image processing; radiological imaging; scuba diving

Authors  Top 
  • Markley, E.
  • Le, D.Q.
  • Germonpré, P., more
  • Balestra, C., more
  • Tillmans, F., more
  • Denoble, P.J.
  • Freiberger, J.J.
  • Moon, R.E.
  • Dayton, P.A.
  • Papadopoulou, V.

Abstract
    Venous gas emboli (VGE) are often quantified as a marker of decompression stress on echocardiograms. Bubble-counting has been proposed as an easy to learn method, but remains time-consuming, rendering large dataset analysis impractical. Computer automation of VGE counting following this method has therefore been suggested as a means to eliminate rater bias and save time. A necessary step for this automation relies on the selection of a frame during late ventricular diastole (LVD) for each cardiac cycle of the recording. Since electrocardiograms (ECG) are not always recorded in field experiments, here we propose a fully automated method for LVD frame selection based on regional intensity minimization. The algorithm is tested on 20 previously acquired echocardiography recordings (from the original bubble-counting publication), half of which were acquired at rest (Rest) and the other half after leg flexions (Flex). From the 7,140 frames analyzed, sensitivity was found to be 0.913 [95% CI: 0.875-0.940] and specificity 0.997 [95% CI: 0.996-0.998]. The method's performance is also compared to that of random chance selection and found to perform significantly better (p<0.0001). No trend in algorithm performance was found with respect to VGE counts, and no significant difference was found between Flex and Rest (p>0.05). In conclusion, full automation of LVD frame selection for the purpose of bubble counting in postdive echocardiography has been established with excellent accuracy, although we caution that high quality acquisitions remain paramount in retaining high reliability.

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