Characterization of androstenedione and 17ß-estradiol metabolism during the proposed critical period of sex differentiation in the tilapia Oreochromis niloticus
Rowell, C.B.; Mair, G.C.; Hines, G.A.; Wibbels, T.; Watts, S.A. (2000). Characterization of androstenedione and 17ß-estradiol metabolism during the proposed critical period of sex differentiation in the tilapia Oreochromis niloticus, in: Norberg, B. et al. (Ed.) Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. pp. 264
In: Norberg, B. et al. (2000). Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. International Symposium on the Reproductive Physiology of Fish, 6. Department of Fisheries and Marine Biology, University of Bergen: Bergen. ISBN 82-7461-048-2. 499 pp., more
In: International Symposium on the Reproductive Physiology of Fish. Museo Nacional de Ciencias Naturales. , more
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| Authors | | Top |
- Rowell, C.B.
- Mair, G.C.
- Hines, G.A.
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| Abstract |
Homogenates derived from mono-sex populations, including XX, XY and YY genotypes, of sexually differentiating 8-13 day post fertilization (dpf) fish were incubated with super(3)H-androstenedione or super(3)h-17 beta -estradiol. Androstenedione was metabolized into at least seven readily identifiable compounds. During this period, testosterone production increased 2 to 3 fold in the XY genotype, but did not increase in XX genotypes, suggesting a sex-specific difference in testosterone synthesis. There was no detectable production of estrone or 17 beta -estradiol from the metabolism of androstenedione. 17 beta -estradiol was metabolized into at least five metabolites including estrone and several unknowns, but was not specific to genotypes. |
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