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Activity of 6-pentadecylsalicylic acid from Ozoroa insignis against marine crustaceans
He, W.; Van Puyvelde, L.; Bosselaers, J.; De Kimpe, N.; Van der Flaas, M.; Roymans, A.; Mathenge, S.G.; Mudida, F.P.; Chalo Mutiso, P.B. (2002). Activity of 6-pentadecylsalicylic acid from Ozoroa insignis against marine crustaceans. Pharm. Biol. 40(1): 74-76. https://dx.doi.org/10.1076/phbi.40.1.74.5862
In: Pharmaceutical Biology. Informa Healthcare: New York. ISSN 1388-0209; e-ISSN 1744-5116, more
Peer reviewed article  

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Authors  Top 
  • He, W.
  • Van Puyvelde, L.
  • Bosselaers, J.
  • De Kimpe, N.
  • Van der Flaas, M.
  • Roymans, A.
  • Mathenge, S.G.
  • Mudida, F.P.
  • Chalo Mutiso, P.B.

Abstract
    Bioassay-guided fractionation of the dichloromethane extract from twigs of Ozoroa insignis using Artemia salina larvae as a model led to the isolation of 6-pentadecylsalicylic acid as the active principle. This is the first report of this so-called antifouling activity for this compound. In addition, this compound may relate to the traditional use of this plant as a herbal remedy for the treatment of urinary schistosomiasis in Africa.

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