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Blood lead, parental marital status and the risk of attention-deficit/hyperactivity disorder in elementary school children: a longitudinal study
Choi, W.-J.; Kwon, H.-J.; Lim, M.H.; Lim, J.-A.; Ha, M. (2016). Blood lead, parental marital status and the risk of attention-deficit/hyperactivity disorder in elementary school children: a longitudinal study. Psychiatry Research 236: 42-46. https://dx.doi.org/10.1016/j.psychres.2016.01.002
In: Psychiatry Research. ELSEVIER IRELAND LTD: Clare. ISSN 0165-1781, more
Peer reviewed article  

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Author keywords
    Attention-deficit/hyperactivity disorder; Lead; Parental marital status; Interaction; Longitudinal

Authors  Top 
  • Choi, W.-J.
  • Kwon, H.-J.
  • Lim, M.H.
  • Lim, J.-A.
  • Ha, M.

Abstract
    The aim of this study was to investigate the blood lead level and parental marital status that might influence the development of attention-deficit/hyperactivity disorder (ADHD) symptoms in school-aged children. The participants in the survey included elementary school children, and they were followed up biennially. The participants' parents or caregivers were administered a questionnaire including ADHD rating scale. Among 2967 who were not suspected to have ADHD at baseline survey, 2195 children who took follow-up test for ADHD were evaluated. The incidence rate of suspected ADHD was 5.0% (107 cases) during the two years of the follow-up period. The geometric mean blood lead level was 1.56 μg/dL. Relative risk ratio for ADHD was estimated using logistic regression analysis. After adjustment for potential confounders, ADHD developed more frequently in children with blood lead levels of >2.17 μg/dL (highest quartile) (RR 1.552, 95% CI 1.002–2.403) and in children with a single parent (RR 1.805, 95% CI 1.002–3.254). The RR was 3.567 (95% CI 1.595–7.980) in children with relatively high blood lead levels (>2.17 μg/dL) from single-parent families, compared with those with low blood lead and a two-parent family. The ADHD risk in association with blood lead level was modified by family status.

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