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[ report an error in this record ] basket (0): add | show Toxicological profile of hydrofluoropolyethers Malinverno, G.; Colombo, I.; Visca, M. (2005). Toxicological profile of hydrofluoropolyethers. Regul. Toxicol. Pharmacol. 41(3): 228-239. https://dx.doi.org/10.1016/j.yrtph.2004.12.003 In: Regulatory Toxicology and Pharmacology. Elsevier: New York, N.Y.. ISSN 0273-2300; e-ISSN 1096-0295, more    Available in  Authors  VLIZ: Non-open access 362667 [ request ] Keyword Toxicology Author keywords Hydrofluoropolyethers; Fluorinated fluids; Risk assessment Authors    Top  Malinverno, G. Colombo, I. Visca, M. Abstract Hydrofluoropolyethers (HFPE) are a family of linear oligomeric fluorinated fluids comprising a chain of difluoromethoxy and tetrafluoroethoxy repeating units with terminal OCF2H end groups, each of which contains an isolated hydrogen atom. These fluids have been designed as low environmental impact substitutes for perfluorinated organic substances in a number of applications including heat transfer and fire suppression agents, and as a solvent. The toxicological profile of these new fluids has been evaluated and is presented in this paper. Acute toxicity tests have been performed on Sprague–Dawley Crl: CD (SD) BR rats using oral, dermal, and inhalation routes. No deaths were recorded even at the highest tested concentrations, and the resultant LD50/LC50 values were >5000