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Tracking complex mixtures of chemicals in our changing environment
Escher, B.I.; Stapleton, H.M.; Schymanski, E.L. (2020). Tracking complex mixtures of chemicals in our changing environment. Science (Wash.) 367(6476): 388-392. https://dx.doi.org/10.1126/science.aay6636
In: Science (Washington). American Association for the Advancement of Science: New York, N.Y. ISSN 0036-8075; e-ISSN 1095-9203, more
Peer reviewed article  

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  • Escher, B.I.
  • Stapleton, H.M.
  • Schymanski, E.L.

Abstract
    Chemicals have improved our quality of life, but the resulting environmental pollution has the potential to cause detrimental effects on humans and the environment. People and biota are chronically exposed to thousands of chemicals from various environmental sources through multiple pathways. Environmental chemists and toxicologists have moved beyond detecting and quantifying single chemicals to characterizing complex mixtures of chemicals in indoor and outdoor environments and biological matrices. We highlight analytical and bioanalytical approaches to isolating, characterizing, and tracking groups of chemicals of concern in complex matrices. Techniques that combine chemical analysis and bioassays have the potential to facilitate the identification of mixtures of chemicals that pose a combined risk.

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