Evaluation of antifouling potential and ecotoxicity of secondary metabolites derived from red algae of the genus Laurencia
Protopapa, M.; Kotsiri, M.; Mouratidis, S.; Roussis, V.; Ioannou, E.; Dedos, S.G. (2019). Evaluation of antifouling potential and ecotoxicity of secondary metabolites derived from red algae of the genus Laurencia. Mar. Drugs 17(11): 646. https://dx.doi.org/10.3390/md17110646
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, more
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| Keywords |
Amphibalanus amphitrite (Darwin, 1854) [WoRMS]; Laurencia J.V.Lamouroux, 1813 [WoRMS]
Marine/Coastal |
| Author keywords |
Laurencia; red algae; biofouling; ecotoxicity; Amphibalanus amphitrite; barnacles; perforenol |
| Authors | | Top |
- Protopapa, M.
- Kotsiri, M.
- Mouratidis, S.
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- Roussis, V.
- Ioannou, E.
- Dedos, S.G.
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| Abstract |
Red algae of the genus Laurencia are known to biosynthesize and secrete an immense variety of secondary metabolites possessing a spectrum of biological activities against bacteria, invertebrates and mammalian cell lines. Following a rigorous cross-species screening process, herein we report the antifouling potential of 25 secondary metabolites derived from species of the genus Laurencia, as well as the thorough evaluation of the ecotoxicity of selected metabolites against non-target marine arthropods and vertebrate cell lines. A number of these secondary metabolites exhibited potent antifouling activity and performed well in all screening tests. Our results show that perforenol (9) possesses similar antifouling activity with that already described for bromosphaerol, which is used herein as a benchmark. |
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