TRP channel blamed for burning cold after a tropical fish meal
In: The EMBO Journal. Nature Publishing Group: Eynsham (P.O. Box 1, Eynsham, Oxford OX8 1JJ). ISSN 0261-4189; e-ISSN 1460-2075, more
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| Abstract |
Ciguatera is one of the most common forms of food poisoning, occurring after consumption of fish contaminated with ciguatoxins. New work by Vetter et al (2012) reveals the key molecular players that underlie the altered temperature sensation associated with ciguatera. In particular, they show that ciguatoxins act on sensory neurons that express TRPA1, an ion channel implicated in the detection of noxious cold. |
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