Minke whale genome and aquatic adaptation in cetaceans
Yim, H.-S.; Cho, Y.S.; Guang, X.; Kang, S.G.; Jeong, J.-Y.; Cha, S.-S.; Oh, H.-M.; Lee, J.-H.; Yang, E.C.; Kwon, K.K.; Kim, Y.J.; Kim, T.W.; Kim, W.; Jeon, J.H.; Kim, S.-J.; Choi, D.H.; Jho, S.; Kim, H.-M.; Ko, J.; Kim, H.; Shin, Y.-A.; Jung, H.-J.; Zheng, Y.; Wang, Z.; Chen, Y.; Chen, M.; Jiang, A.; Li, E.; Zhang, S.; Hou, H.; Kim, T.H.; Yu, L.; Liu, S.; Ahn, K.; Cooper, J.; Park, S.-G.; Hong, C.P.; Jin, W.; Kim, H.-S.; Park, C.; Lee, K.; Chun, S.; Morin, P.A.; O'Brien, S.J.; Lee, H.; Kimura, J.; Moon, D.Y.; Manica, A.; Edwards, J.; Kim, B.C.; Kim, S.; Wang, J.; Bhak, J.; Lee, H.S.; Lee, J.-H. (2014). Minke whale genome and aquatic adaptation in cetaceans. Nature Gen. 46(1): 88-92. https://dx.doi.org/10.1038/ng.2835
In: Nature Genetics. Nature Publishing Group: New York, NY. ISSN 1061-4036; e-ISSN 1546-1718, more
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| Keywords |
Biological phenomena > Adaptations
Genomes
Balaenoptera acutorostrata Lacépède, 1804 [WoRMS]; Balaenoptera bonaerensis Burmeister, 1867 [WoRMS]; Cetacea [WoRMS]
Marine/Coastal |
| Author keywords |
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| Authors | | Top |
- Yim, H.-S.
- Cho, Y.S.
- Guang, X.
- Kang, S.G.
- Jeong, J.-Y.
- Cha, S.-S.
- Oh, H.-M.
- Lee, J.-H.
- Yang, E.C.
- Kwon, K.K.
- Kim, Y.J.
- Kim, T.W.
- Kim, W.
- Jeon, J.H.
- Kim, S.-J.
- Choi, D.H.
- Jho, S.
- Kim, H.-M.
- Ko, J.
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- Kim, H.
- Shin, Y.-A.
- Jung, H.-J.
- Zheng, Y.
- Wang, Z.
- Chen, Y.
- Chen, M.
- Jiang, A.
- Li, E.
- Zhang, S.
- Hou, H.
- Kim, T.H.
- Yu, L.
- Liu, S.
- Ahn, K.
- Cooper, J.
- Park, S.-G.
- Hong, C.P.
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- Jin, W.
- Kim, H.-S.
- Park, C.
- Lee, K.
- Chun, S.
- Morin, P.A.
- O'Brien, S.J.
- Lee, H.
- Kimura, J.
- Moon, D.Y.
- Manica, A.
- Edwards, J.
- Kim, B.C.
- Kim, S.
- Wang, J.
- Bhak, J.
- Lee, H.S.
- Lee, J.-H.
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| Abstract |
The shift from terrestrial to aquatic life by whales was a substantial evolutionary event. Here we report the whole-genome sequencing and de novo assembly of the minke whale genome, as well as the whole-genome sequences of three minke whales, a fin whale, a bottlenose dolphin and a finless porpoise. Our comparative genomic analysis identified an expansion in the whale lineage of gene families associated with stress-responsive proteins and anaerobic metabolism, whereas gene families related to body hair and sensory receptors were contracted. Our analysis also identified whale-specific mutations in genes encoding antioxidants and enzymes controlling blood pressure and salt concentration. Overall the whale-genome sequences exhibited distinct features that are associated with the physiological and morphological changes needed for life in an aquatic environment, marked by resistance to physiological stresses caused by a lack of oxygen, increased amounts of reactive oxygen species and high salt levels |
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