A red orange extract modulates the vascular response to a recreational dive: a pilot study on the effect of anthocyanins on the physiological consequences of scuba diving
Balestra, C.; Cimino, F.; Theunissen, S.; Snoeck, T.; Provyn, S.; Canali, R.; Bonina, A.; Virgili, F. (2016). A red orange extract modulates the vascular response to a recreational dive: a pilot study on the effect of anthocyanins on the physiological consequences of scuba diving. Nat. Prod. Res. 30(18): 2101-2106. https://dx.doi.org/10.1080/14786419.2015.1107062
In: Natural Product Research. Taylor & Francis: Abingdon. ISSN 1478-6419; e-ISSN 1478-6427, more
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| Author keywords |
Diving; anthocyanins; endothelial dysfunction; flow-mediated dilation;body water |
| Authors | | Top |
- Balestra, C., more
- Cimino, F.
- Theunissen, S., more
- Snoeck, T.
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- Provyn, S., more
- Canali, R.
- Bonina, A.
- Virgili, F.
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| Abstract |
Nutritional antioxidants have been proposed as an expedient strategy to counter the potentially deleterious effects of scuba diving on endothelial function, flow-mediated dilation (FMD) and heart function. Sixteen volunteers performing a single standard dive (20min at 33m) according to US Navy diving procedures were randomly assigned to two groups: one was administered with two doses of 200mg of an anthocyanins (AC)-rich extract from red oranges, 12 and 4h before diving. Anthocyanins supplementation significantly modulated the effects of diving on haematocrit, body water distribution and FMD. AC administration significantly reduces the potentially harmful endothelial effects of a recreational single dive. The lack of any significant effect on the most common markers of plasma antioxidant capacity suggests that the mechanism underlying this protective activity is independent of the putative antioxidant effect of AC and possibly involves cellular signalling modulation of the response to high oxygen. |
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