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Estrogenic effects of Di-N-butyl phthalate in juvenile Atlantic salmon (Salmo salar)
Tollefsen, K.-E.; Frydenlund, J.; Stenersen, J. (2000). Estrogenic effects of Di-N-butyl phthalate in juvenile Atlantic salmon (Salmo salar), in: Norberg, B. et al. (Ed.) Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. pp. 371
In: Norberg, B. et al. (2000). Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. International Symposium on the Reproductive Physiology of Fish, 6. Department of Fisheries and Marine Biology, University of Bergen: Bergen. ISBN 82-7461-048-2. 499 pp., meer
In: International Symposium on the Reproductive Physiology of Fish. Museo Nacional de Ciencias Naturales. , meer
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  • Tollefsen, K.-E.
  • Frydenlund, J.
  • Stenersen, J.
Abstract
    Di-n-butyl phthalate (DBP) is able to compete for binding sites at the hepatic estrogen receptor (ER) and the plasma sex-steroid binding protein (SBP) from Atlantic salmon (Salmo salar) at high concentrations. Probably due to a combination of SBP-binding and low affinity for the ER, DBP is not able to induce the estrogenic biomarkers vitellogenin and Zona Radiata proteins in vivo.
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